| Week of 5/16 |
| San Lorenzo 2 Flamengo 1 |
| 9:45 PM Wed | 100.0* | Chance in playoffs | 100.0* | Average seed |
| San Lorenzo | In | | +1.2 | |
| Flamengo | Out | | -1.2 | |
|
| Universidad Catolica 2 Atletico-PR 3 |
| 9:45 PM Wed | 100.0* | Chance in playoffs | 100.0* | Average seed |
| San Lorenzo | -6.3 | | | |
| Atletico-PR | In | | +1.0 | |
| Flamengo | -23.5 | | -0.3 | |
| Universidad Catolica | Out | | -0.6 | |
|
| Independiente Medellin 1 Emelec 2 |
| 11:15 PM Tue | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Emelec | +33.5 | | +0.6 | |
| Independiente Medellin | -38.5 | | -0.7 | |
| Melgar | +5.0 | | | |
|
| Lanus 3 Chapecoense 0 |
| 9:45 PM Wed | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Lanus | In | | +0.4 | |
| Nacional | +11.1 | | | |
| Chapecoense | Out | | -0.5 | |
| Zulia | -8.7 | | | |
|
| Sporting Cristal 0 Santa Fe 2 |
| 7:30 PM Wed | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Santos | -1.2 | | | |
| The Strongest | -10.4 | | | |
| Santa Fe | +21.0 | | +0.6 | |
| Sporting Cristal | Out | | -0.4 | |
|
| Botafogo 1 Atletico Nacional 0 |
| 9:45 PM Thu | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Botafogo | In | | +0.4 | |
| Barcelona | | | -0.2 | |
| Estudiantes | Out | | | |
| Atletico Nacional | Out | | -0.3 | |
|
| Melgar 2 River Plate 3 |
| 9:00 PM Thu | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Emelec | +8.7 | | +0.2 | |
| Independiente Medellin | +8.6 | | +0.2 | |
| Melgar | Out | | -0.4 | |
|
| The Strongest 1 Santos 1 |
| 7:30 PM Wed | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Santos | In | | +0.1 | |
| The Strongest | -0.4 | | -0.0 | |
| Santa Fe | -5.9 | | | |
| Sporting Cristal | -4.9 | | | |
|
| Barcelona 0 Estudiantes 3 |
| 7:30 PM Thu | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Botafogo | -7.8 | | | |
| Barcelona | | | -0.2 | |
| Estudiantes | +10.8 | | +0.4 | |
| Atletico Nacional | -3.0 | | -0.2 | |
|
| Zulia 0 Nacional 0 |
| 7:30 PM Tue | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Lanus | -1.0 | | | |
| Nacional | +6.2 | | +0.2 | |
| Chapecoense | +0.5 | | | |
| Zulia | -5.6 | | -0.2 | |
|
| Atletico-MG 4 Godoy Cruz 1 |
| 9:45 PM Tue | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Atletico-MG | | | +0.6 | |
| Godoy Cruz | | | -0.6 | |
|
| Week of 5/24 |
| Palmeiras 3 Atletico Tucuman 1 |
| 9:45 PM Wed | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Palmeiras | In | | +0.7 | |
| Jorge Wilstermann | In | | | |
| Atletico Tucuman | Out | | -0.5 | |
|
| Guarani 0 Deportes Iquique 0 |
| 9:45 PM Thu | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Gremio | -20.1 | | | |
| Guarani | In | | +0.4 | |
| Deportes Iquique | -13.9 | | -0.4 | |
|
| Emelec 3 Melgar 0 |
| 7:30 PM Thu | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Emelec | In | | +0.3 | |
| Independiente Medellin | Out | | -0.2 | |
|
| River Plate 1 Independiente Medellin 2 |
| 7:30 PM Thu | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Emelec | -29.7 | | -0.3 | |
| Independiente Medellin | +29.7 | | +0.4 | |
|
| Penarol 2 Jorge Wilstermann 0 |
| 9:45 PM Wed | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Palmeiras | In | | +0.3 | |
| Jorge Wilstermann | -23.5 | | -0.5 | |
| Atletico Tucuman | +2.9 | | +0.2 | |
|
| Gremio 4 Zamora 0 |
| 9:45 PM Thu | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Gremio | In | | +0.6 | |
| Guarani | -4.0 | | -0.3 | |
| Deportes Iquique | -7.6 | | -0.3 | |
|
| Atletico Nacional 3 Barcelona 1 |
| 9:45 PM Thu | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Botafogo | | | +0.3 | |
| Barcelona | | | -0.3 | |
| Estudiantes | | | -0.2 | |
| Atletico Nacional | | | +0.2 | |
|
| Estudiantes 1 Botafogo 0 |
| 9:45 PM Thu | 100.0* | Chance in playoffs | 100.0* | Average seed |
| Botafogo | | | -0.3 | |
| Barcelona | | | +0.3 | |