| Week of 4/23 |
| Jorge Wilstermann 3 Athletico-PR 2 |
| 7:15 PM Wed | 100.0* | Lottery seed |
| Athletico-PR | +3.6 | |
| Jorge Wilstermann | -4.9 | |
|
| San Jose 3 Penarol 1 |
| 9:30 PM Wed | 100.0* | Lottery seed |
| Flamengo | -1.0 | |
| Penarol | +3.8 | |
| San Jose | -4.4 | |
|
| Junior 1 San Lorenzo 0 |
| 9:00 PM Thu | 100.0* | Lottery seed |
| Palmeiras | -1.0 | |
| San Lorenzo | +2.9 | |
| Junior | -4.2 | |
|
| Zamora 2 Cerro Porteno 1 |
| 5:00 PM Thu | 100.0* | Lottery seed |
| Cerro Porteno | +2.9 | |
| Nacional | -1.5 | |
| Zamora | -4.0 | |
|
| Libertad 0 Gremio 2 |
| 7:15 PM Tue | 100.0* | Lottery seed |
| Libertad | +2.3 | |
| Gremio | -4.3 | |
| Universidad Catolica | +1.0 | |
|
| LDU 2 Flamengo 1 |
| 9:30 PM Wed | 100.0* | Lottery seed |
| Flamengo | +3.9 | |
| LDU | -3.9 | |
|
| Godoy Cruz 2 Sporting Cristal 0 |
| 9:30 PM Tue | 100.0* | Lottery seed |
| Godoy Cruz | -3.6 | |
| Sporting Cristal | +3.5 | |
|
| Palestino 0 River Plate 2 |
| 7:15 PM Wed | 100.0* | Lottery seed |
| River Plate | -3.0 | |
| Palestino | +2.8 | |
|
| Huracan 1 Emelec 2 |
| 7:15 PM Tue | 100.0* | Lottery seed |
| Emelec | -2.7 | |
| Deportivo Lara | +0.4 | |
| Huracan | +1.9 | |
|
| Atletico-MG 0 Nacional 1 |
| 9:30 PM Tue | 100.0* | Lottery seed |
| Cerro Porteno | +0.3 | |
| Nacional | -1.2 | |
| Atletico-MG | +1.3 | |
|
| Deportes Tolima 2 Boca Juniors 2 |
| 9:30 PM Wed | 100.0* | Lottery seed |
| Boca Juniors | +1.6 | |
| Deportes Tolima | -0.7 | |
|
| Alianza Lima 0 Internacional 1 |
| 9:30 PM Wed | 100.0* | Lottery seed |
| Internacional | -1.0 | |
| River Plate | +0.2 | |
| Alianza Lima | +0.8 | |
|
| Deportivo Lara 0 Cruzeiro 2 |
| 5:00 PM Tue | 100.0* | Lottery seed |
| Cruzeiro | -0.6 | |
| Deportivo Lara | +0.8 | |
|
| Melgar 0 Palmeiras 4 |
| 11:00 PM Thu | 100.0* | Lottery seed |
| Palmeiras | -0.6 | |
| San Lorenzo | +0.2 | |
| Melgar | +0.7 | |
|
| Rosario Central 1 Universidad Catolica 1 |
| 7:15 PM Wed | 100.0* | Lottery seed |
| Universidad Catolica | +0.7 | |
| Rosario Central | +0.2 | |
|
| Universidad de Concepcion 3 Olimpia 3 |
| 7:15 PM Tue | 100.0* | Lottery seed |
| Olimpia | +0.7 | |
| Universidad de Concepcion | -0.1 | |
|
| Week of 5/7 |
| Olimpia 0 Sporting Cristal 1 |
| 7:15 PM Thu | 100.0* | Lottery seed |
| Libertad | -0.6 | |
| Flamengo | -0.6 | |
| Olimpia | +4.6 | |
| Godoy Cruz | -1.4 | |
| Sporting Cristal | -6.6 | |
| Melgar | +0.9 | |
| Atletico-MG | +0.9 | |
| Rosario Central | +0.6 | |
| Deportivo Lara | +0.6 | |
| Huracan | +0.6 | |
|
| Huracan 3 Deportivo Lara 0 |
| 7:15 PM Wed | 100.0* | Lottery seed |
| Emelec | -3.3 | |
| Deportivo Lara | +5.9 | |
| Huracan | -3.0 | |
| Zamora | +0.8 | |
|
| Rosario Central 2 Libertad 1 |
| 7:15 PM Wed | 100.0* | Lottery seed |
| Internacional | -0.6 | |
| Cerro Porteno | -0.9 | |
| Libertad | +3.3 | |
| Rosario Central | -4.3 | |
| Zamora | +0.9 | |
|
| Boca Juniors 2 Athletico-PR 1 |
| 9:30 PM Thu | 100.0* | Lottery seed |
| Libertad | -0.4 | |
| Boca Juniors | -5.7 | |
| Athletico-PR | +5.7 | |
| Emelec | +0.2 | |
|
| Cruzeiro 1 Emelec 2 |
| 7:15 PM Wed | 100.0* | Lottery seed |
| Emelec | -4.9 | |
| Deportivo Lara | +1.6 | |
|
| Junior 0 Melgar 1 |
| 9:30 PM Wed | 100.0* | Lottery seed |
| Melgar | -4.5 | |
| Atletico-MG | +0.5 | |
| Zamora | -0.7 | |
| Junior | +3.6 | |
|
| Zamora 1 Atletico-MG 2 |
| 7:15 PM Tue | 100.0* | Lottery seed |
| Atletico-MG | -4.8 | |
| Zamora | +4.6 | |
|
| Jorge Wilstermann 0 Deportes Tolima 2 |
| 9:30 PM Thu | 100.0* | Lottery seed |
| Deportes Tolima | -3.6 | |
| Palestino | +0.2 | |
| Universidad Catolica | +0.2 | |
| Melgar | +0.2 | |
| Rosario Central | -0.4 | |
| Deportivo Lara | -0.5 | |
| Jorge Wilstermann | +3.5 | |
|
| LDU 4 San Jose 0 |
| 9:30 PM Wed | 100.0* | Lottery seed |
| Flamengo | +0.6 | |
| LDU | -2.7 | |
| Penarol | +0.8 | |
| San Jose | +1.8 | |
|
| Godoy Cruz 1 Universidad de Concepcion 0 |
| 7:15 PM Thu | 100.0* | Lottery seed |
| Godoy Cruz | -2.7 | |
| Universidad Catolica | -0.2 | |
| Melgar | -0.2 | |
| Universidad de Concepcion | +2.7 | |
|
| Nacional 1 Cerro Porteno 1 |
| 7:15 PM Tue | 100.0* | Lottery seed |
| Cerro Porteno | -2.6 | |
| Nacional | +2.9 | |
|
| Palmeiras 1 San Lorenzo 0 |
| 9:30 PM Wed | 100.0* | Lottery seed |
| Palmeiras | -2.2 | |
| Internacional | +0.5 | |
| River Plate | -0.5 | |
| San Lorenzo | +2.3 | |
|
| Gremio 2 Universidad Catolica 0 |
| 7:15 PM Wed | 100.0* | Lottery seed |
| Gremio | -2.5 | |
| Palestino | -0.4 | |
| Universidad Catolica | +2.3 | |
|
| Penarol 0 Flamengo 0 |
| 9:30 PM Wed | 100.0* | Lottery seed |
| Flamengo | -1.8 | |
| LDU | +0.8 | |
| Penarol | +1.2 | |
|
| Alianza Lima 1 Palestino 2 |
| 9:30 PM Tue | 100.0* | Lottery seed |
| Palestino | -2.1 | |
| Alianza Lima | +0.7 | |
|
| River Plate 2 Internacional 2 |
| 9:30 PM Tue | 100.0* | Lottery seed |
| Internacional | +0.2 | |