| Week of 4/6 |
| Jaguares 1 Internacional 0 |
| Wed | 100.0* | Lottery seed |
| Internacional | +3.8 | |
| Jaguares | -6.7 | |
| Emelec | +1.7 | |
|
| Nacional 2 Fluminense 0 |
| Wed | 100.0* | Lottery seed |
| America | -0.2 | |
| Fluminense | +6.1 | |
| Nacional | -6.3 | |
|
| America 2 Argentinos Juniors 1 |
| Wed | 100.0* | Lottery seed |
| America | -5.9 | |
| Fluminense | +0.3 | |
| Argentinos Juniors | +4.9 | |
|
| Santos 3 Colo-Colo 2 |
| Wed | 100.0* | Lottery seed |
| Santos | -4.6 | |
| Colo-Colo | +3.9 | |
|
| Penarol 0 Independiente 1 |
| Tue | 100.0* | Lottery seed |
| LDU de Quito | -0.7 | |
| Penarol | +3.1 | |
| Independiente | -3.2 | |
|
| LDU de Quito 2 Godoy Cruz 0 |
| Tue | 100.0* | Lottery seed |
| LDU de Quito | -4.6 | |
| Penarol | +1.0 | |
| Godoy Cruz | +3.9 | |
|
| Union Espanola 1 Caracas 2 |
| Wed | 100.0* | Lottery seed |
| Caracas | -4.0 | |
| Union Espanola | +4.0 | |
|
| Colo-Colo 2 Deportivo Tachira 1 |
| Tue | 100.0* | Lottery seed |
| Cerro Porteno | +0.4 | |
| Santos | +0.6 | |
| Colo-Colo | -3.4 | |
| Deportivo Tachira | +1.8 | |
|
| Jorge Wilstermann 0 Emelec 0 |
| Thu | 100.0* | Lottery seed |
| Internacional | -0.8 | |
| Jaguares | -1.1 | |
| Emelec | +3.3 | |
| Jorge Wilstermann | -0.2 | |
|
| Deportivo Tachira 0 Cerro Porteno 2 |
| Wed | 100.0* | Lottery seed |
| Cerro Porteno | -2.3 | |
| Deportivo Tachira | +2.1 | |
|
| Gremio 2 Junior 0 |
| Thu | 100.0* | Lottery seed |
| Junior | +1.0 | |
| Gremio | -2.0 | |
|
| Universidad Catolica 0 Velez Sarsfield 0 |
| Thu | 100.0* | Lottery seed |
| Universidad Catolica | +0.0 | |
| Velez Sarsfield | +1.4 | |
| Caracas | -1.0 | |
|
| Week of 4/13 |
| Cerro Porteno 1 Santos 2 |
| Thu | 100.0* | Lottery seed |
| Cerro Porteno | +5.3 | |
| Santos | -7.6 | |
| Colo-Colo | +0.7 | |
|
| Universidad San Martin 0 Once Caldas 2 |
| Tue | 100.0* | Lottery seed |
| Penarol | -0.5 | |
| Once Caldas | -6.9 | |
| Universidad San Martin | +6.9 | |
| Leon de Huanuco | +0.5 | |
|
| Jorge Wilstermann 2 Jaguares 1 |
| Tue | 100.0* | Lottery seed |
| Internacional | -1.5 | |
| Jaguares | +6.5 | |
| Emelec | -1.2 | |
| Jorge Wilstermann | -1.1 | |
|
| Oriente Petrolero 3 Gremio 0 |
| Thu | 100.0* | Lottery seed |
| Junior | -1.3 | |
| Gremio | +3.0 | |
| Oriente Petrolero | -3.7 | |
|
| Caracas 0 Velez Sarsfield 3 |
| Thu | 100.0* | Lottery seed |
| Universidad Catolica | +0.3 | |
| Velez Sarsfield | -6.2 | |
| Caracas | +4.8 | |
| Independiente | +0.3 | |
| Tolima | +0.3 | |
|
| Universidad Catolica 2 Union Espanola 1 |
| Thu | 100.0* | Lottery seed |
| Universidad Catolica | -4.2 | |
| Velez Sarsfield | +0.8 | |
| Estudiantes | +0.5 | |
| Caracas | +1.1 | |
| Union Espanola | +1.8 | |
|
| Internacional 2 Emelec 0 |
| Tue | 100.0* | Lottery seed |
| Internacional | -3.5 | |
| Junior | +0.4 | |
| Jaguares | +0.9 | |
| Emelec | +3.1 | |
|
| Junior 1 Leon de Huanuco 1 |
| Thu | 100.0* | Lottery seed |
| Junior | +3.3 | |
| Gremio | -2.5 | |
| Leon de Huanuco | -0.4 | |
|
| Libertad 2 San Luis 0 |
| Tue | 100.0* | Lottery seed |
| Libertad | -1.1 | |
| Junior | +0.4 | |
| Once Caldas | -0.5 | |
| Oriente Petrolero | -0.4 | |
| Universidad San Martin | -0.4 | |
| San Luis | +2.3 | |
|
| Guarani 0 Tolima 2 |
| Wed | 100.0* | Lottery seed |
| Tolima | -2.5 | |
| Godoy Cruz | +0.4 | |
| Guarani | +0.5 | |
|
| Estudiantes 0 Cruzeiro 3 |
| Wed | 100.0* | Lottery seed |
| Cruzeiro | -0.5 | |
| Estudiantes | +0.7 | |
|
| Week of 4/20 |
| Argentinos Juniors 2 Fluminense 4 |
| Wed | 100.0* | Lottery seed |
| America | -1.2 | |
| Estudiantes | -0.5 | |
| Fluminense | -6.6 | |
| Nacional | -0.5 | |
| Argentinos Juniors | +8.2 | |
| Oriente Petrolero | +0.7 | |
| Universidad San Martin | +0.5 | |
|
| Colo-Colo 2 Cerro Porteno 3 |
| Wed | 100.0* | Lottery seed |
| Cerro Porteno | -5.0 | |
| Colo-Colo | +4.3 | |
|
| Santos 3 Deportivo Tachira 1 |
| Wed | 100.0* | Lottery seed |
| Cerro Porteno | +0.9 | |
| Santos | -3.8 | |
| Estudiantes | +0.4 | |
| Colo-Colo | +0.9 | |
| Leon de Huanuco | -0.2 | |
| Union Espanola | -0.2 | |
| Jorge Wilstermann | -0.2 | |
| Deportivo Tachira | +0.8 | |
|
| Nacional 0 America 0 |
| Wed | 100.0* | Lottery seed |
| Universidad Catolica | -0.4 | |
| America | -0.1 | |
| Fluminense | +0.5 | |
| Nacional | +1.0 | |
| Independiente | +0.4 | |
| Emelec | +0.4 | |
| Tolima | +0.4 | |
| Argentinos Juniors | -0.8 | |