| Tuesday |
| Estudiantes 1 Alianza Lima 0 |
| 100.0* | Lottery seed |
| Estudiantes | -5.6 | |
| Alianza Lima | +4.2 | |
| Cruzeiro | +0.6 | |
| Universitario | +0.3 | |
|
| Bolivar 2 Juan Aurich 0 |
| 100.0* | Lottery seed |
| Lanus | -0.4 | |
| Cerro | -0.3 | |
| Colo-Colo | -0.4 | |
| Monterrey | -0.3 | |
| Juan Aurich | +2.7 | |
| Morelia | -0.3 | |
| Bolivar | -2.0 | |
| Cerro Porteno | +0.3 | |
| Emelec | +0.3 | |
| Caracas | +0.3 | |
| Deportivo Italia | +0.3 | |
| Blooming | +0.3 | |
|
| Wednesday |
| Banfield 4 Deportivo Cuenca 1 |
| 100.0* | Lottery seed |
| Nacional | +2.3 | |
| Banfield | -4.0 | |
| Universitario | +0.4 | |
| Juan Aurich | -0.4 | |
| Morelia | -0.3 | |
| Bolivar | -0.5 | |
| Deportivo Cuenca | +2.8 | |
|
| Sao Paulo 1 Once Caldas 0 |
| 100.0* | Lottery seed |
| Sao Paulo | -6.0 | |
| Estudiantes | +0.2 | |
| Velez Sarsfield | +0.2 | |
| Libertad | +0.2 | |
| Once Caldas | +4.7 | |
| Universitario | +0.3 | |
|
| Nacional 2 Morelia 0 |
| 100.0* | Lottery seed |
| Libertad | +0.4 | |
| Nacional | -2.6 | |
| Banfield | +0.7 | |
| Lanus | -0.3 | |
| Colo-Colo | -0.4 | |
| Monterrey | -0.3 | |
| Juan Aurich | -0.6 | |
| Morelia | +3.2 | |
| Deportivo Cuenca | -0.3 | |
|
| Flamengo 3 Caracas 2 |
| 100.0* | Lottery seed |
| Universitario | +0.5 | |
| Flamengo | -3.4 | |
| Universidad Catolica | +0.9 | |
| Bolivar | -0.4 | |
| Cerro Porteno | -0.3 | |
| Emelec | -0.3 | |
| Caracas | +1.5 | |
|
| Nacional-PAR 2 Monterrey 0 |
| 100.0* | Lottery seed |
| Lanus | -0.4 | |
| Cerro | -0.3 | |
| Colo-Colo | -0.4 | |
| Monterrey | +2.7 | |
| Nacional-PAR | -1.8 | |
| Cerro Porteno | +0.3 | |
| Emelec | +0.3 | |
| Deportivo Italia | +0.4 | |
| Blooming | +0.4 | |
|
| Universidad de Chile 0 Universidad Catolica 0 |
| 100.0* | Lottery seed |
| Corinthians | -0.2 | |
| Estudiantes | -0.4 | |
| Velez Sarsfield | -0.4 | |
| Libertad | -0.4 | |
| Universidad de Chile | +1.9 | |
| Flamengo | -0.2 | |
| Lanus | -0.2 | |
| Colo-Colo | -0.2 | |
| Universidad Catolica | +0.5 | |
|
| Thursday |
| Internacional 3 Deportivo Quito 0 |
| 100.0* | Lottery seed |
| Velez Sarsfield | -0.3 | |
| Libertad | -0.0 | |
| Internacional | -5.8 | |
| Nacional | +0.1 | |
| Universidad de Chile | +0.2 | |
| Deportivo Quito | +6.8 | |
| Cerro | -0.3 | |
|
| Corinthians 1 Independiente Medellin 0 |
| 100.0* | Lottery seed |
| Corinthians | -1.4 | |
| Sao Paulo | +0.4 | |
| Estudiantes | +0.4 | |
| Velez Sarsfield | +0.4 | |
| Racing | -1.0 | |
| Colo-Colo | -0.2 | |
| Universidad Catolica | -0.4 | |
| Independiente Medellin | +2.8 | |
| Monterrey | -0.4 | |
|
| Cerro Porteno 0 Racing 0 |
| 100.0* | Lottery seed |
| Universitario | -0.3 | |
| Flamengo | -0.3 | |
| Racing | +0.9 | |
| Independiente Medellin | -0.2 | |
| Bolivar | -0.4 | |
| Deportivo Cuenca | -0.4 | |
| Nacional-PAR | -0.4 | |
| Cerro Porteno | +0.5 | |
| Caracas | +0.4 | |
|
| Cerro 0 Emelec 0 |
| 100.0* | Lottery seed |
| Internacional | -0.2 | |
| Universitario | -0.2 | |
| Flamengo | -0.3 | |
| Deportivo Quito | -0.3 | |
| Lanus | +0.3 | |
| Cerro | -0.1 | |
| Colo-Colo | +0.4 | |
| Universidad Catolica | +0.4 | |
| Bolivar | -0.4 | |
| Deportivo Cuenca | -0.4 | |
| Nacional-PAR | -0.4 | |
| Emelec | +0.5 | |
| Caracas | +0.4 | |