| Week of 4/8 |
| Audax Italiano 1 Sao Paulo 0 |
| Thu | 100.0* | Lottery seed |
| Sao Paulo | +4.3 | |
| Audax Italiano | -5.7 | |
|
| Sportivo Luqueno 1 Atletico Nacional 3 |
| Thu | 100.0* | Lottery seed |
| Atletico Nacional | -6.4 | |
| Sportivo Luqueno | +5.1 | |
| Audax Italiano | +0.5 | |
|
| Colo-Colo 2 Union Maracaibo 0 |
| Thu | 100.0* | Lottery seed |
| Atlas | +0.9 | |
| Boca Juniors | +0.7 | |
| Colo-Colo | -5.6 | |
| Union Maracaibo | +3.4 | |
|
| Chivas Guadalajara 3 Santos 2 |
| Wed | 100.0* | Lottery seed |
| Cucuta Deportivo | -0.9 | |
| Santos | +4.5 | |
| Chivas Guadalajara | -4.3 | |
|
| Cienciano 0 Flamengo 3 |
| Wed | 100.0* | Lottery seed |
| Flamengo | -5.8 | |
| Nacional | +0.9 | |
| Cienciano | +4.8 | |
|
| San Jose 2 Cucuta Deportivo 4 |
| Tue | 100.0* | Lottery seed |
| Cucuta Deportivo | -4.0 | |
| Santos | +0.3 | |
| San Jose | +4.2 | |
|
| Atlas 3 Boca Juniors 1 |
| Wed | 100.0* | Lottery seed |
| Atlas | -5.3 | |
| Boca Juniors | +5.4 | |
|
| Arsenal 2 Fluminense 0 |
| Wed | 100.0* | Lottery seed |
| Fluminense | +2.2 | |
| LDU | -0.8 | |
| Arsenal | -3.6 | |
|
| Libertad 3 LDU 1 |
| Tue | 100.0* | Lottery seed |
| Fluminense | -0.9 | |
| LDU | +2.1 | |
| Libertad | -1.9 | |
|
| Week of 4/15 |
| Universidad Catolica 2 America 0 |
| Thu | 100.0* | Lottery seed |
| River Plate | -1.1 | |
| America | +7.1 | |
| Universidad Catolica | -5.8 | |
| Arsenal | +0.5 | |
| Deportivo Cuenca | +0.4 | |
| Universidad San Martin | -0.7 | |
|
| Estudiantes 2 Deportivo Cuenca 0 |
| Tue | 100.0* | Lottery seed |
| Estudiantes | -5.9 | |
| Lanus | +0.4 | |
| Deportivo Cuenca | +7.2 | |
| Danubio | -0.6 | |
|
| River Plate 5 Universidad San Martin 0 |
| Thu | 100.0* | Lottery seed |
| River Plate | -6.8 | |
| America | +1.2 | |
| Universidad Catolica | +0.2 | |
| Arsenal | -0.3 | |
| Universidad San Martin | +5.3 | |
|
| Danubio 1 Lanus 2 |
| Tue | 100.0* | Lottery seed |
| Estudiantes | +1.5 | |
| Lanus | -6.6 | |
| Deportivo Cuenca | +1.3 | |
| Danubio | +4.5 | |
|
| San Lorenzo 3 Caracas 0 |
| Thu | 100.0* | Lottery seed |
| San Lorenzo | -6.3 | |
| Caracas | +5.9 | |
|
| San Jose 0 Chivas Guadalajara 3 |
| Wed | 100.0* | Lottery seed |
| Santos | +1.2 | |
| Chivas Guadalajara | -4.9 | |
| Danubio | -0.6 | |
| San Jose | +3.9 | |
|
| Santos 2 Cucuta Deportivo 1 |
| Wed | 100.0* | Lottery seed |
| Estudiantes | -0.6 | |
| Cucuta Deportivo | +2.9 | |
| Santos | -5.0 | |
| Lanus | +0.6 | |
| Chivas Guadalajara | +0.8 | |
|
| Libertad 1 Arsenal 2 |
| Wed | 100.0* | Lottery seed |
| Arsenal | -4.6 | |
| Danubio | -0.6 | |
| Libertad | +3.3 | |
|
| Real Potosi 5 Cruzeiro 1 |
| Thu | 100.0* | Lottery seed |
| Cruzeiro | +2.5 | |
| Real Potosi | -3.1 | |
| Deportivo Cuenca | +0.6 | |
| Danubio | +0.4 | |
| San Jose | +0.4 | |
| Libertad | +0.4 | |
|
| Fluminense 1 LDU 0 |
| Thu | 100.0* | Lottery seed |
| Fluminense | -4.9 | |
| Santos | -0.2 | |
| LDU | +5.2 | |
|
| Week of 4/22 |
| Sportivo Luqueno 4 Audax Italiano 1 |
| Wed | 100.0* | Lottery seed |
| Sao Paulo | -1.6 | |
| San Lorenzo | -0.3 | |
| America | -0.3 | |
| Atletico Nacional | -1.7 | |
| Sportivo Luqueno | -3.8 | |
| Audax Italiano | +6.0 | |
| Real Potosi | +0.6 | |
| Deportivo Cuenca | +0.6 | |
| Universidad San Martin | +0.6 | |
| Danubio | +0.4 | |
|
| Sao Paulo 1 Atletico Nacional 0 |
| Wed | 100.0* | Lottery seed |
| Sao Paulo | -8.2 | |
| Atletico Nacional | +7.7 | |
|
| Nacional 3 Cienciano 1 |
| Wed | 100.0* | Lottery seed |
| Nacional | -7.2 | |
| Arsenal | -0.3 | |
| Cienciano | +5.3 | |
|
| Flamengo 2 Coronel Bolognesi 0 |
| Wed | 100.0* | Lottery seed |
| Flamengo | -6.2 | |
| Nacional | +2.0 | |
| Cienciano | +0.5 | |
| Danubio | -0.4 | |
| San Jose | -0.4 | |
| Libertad | -0.6 | |
| Coronel Bolognesi | +1.8 | |
|
| Boca Juniors 3 Union Maracaibo 0 |
| Tue | 100.0* | Lottery seed |
| Atlas | +0.8 | |
| Boca Juniors | -6.3 | |
| Colo-Colo | +1.3 | |
| Arsenal | +0.6 | |
| Danubio | -0.4 | |
| San Jose | -0.4 | |
| Libertad | -0.4 | |
| Union Maracaibo | +1.7 | |
|
| Colo-Colo 1 Atlas 1 |
| Tue | 100.0* | Lottery seed |
| River Plate | -0.7 | |
| Atlas | -3.0 | |
| Colo-Colo | +3.4 | |